By Nik Money
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April 3, 2024
Species perform life cycles by transmitting distinctive collections of genes from one generation to the next. Individuals contribute to this process if they serve as biological parents, but there is no cycle for each of them, each human being, just a beginning and an end. Cells behaving as amoebas are conductors for the whole journey, sculpting the developing fetus, protecting the body from bacterial and fungal infection, repairing wounds, and removing worn out cells. Amoebas also destroy cancer cells until they turn cancerous themselves, spread tumors across the body, and extinguish one in six of us. All of these amoeboid human cells dig deep into the billion-year-old instructions in their genomes to activate the machinery for forming pseudopodia and flowing and feeding from place to place. From birth to death, womb to tomb, the body calls on its ancient amoeboid ancestry, just as it relies on its ciliary history to make sperm cells and the hairy cells that line the lungs and other organs. We are gigantic amalgams of the single-celled microbes that learned to crawl and swim in the mud and sunlit pools of the Precambrian.